Phytochemical investigation of premna odorata blanco, lamiaceae, leaves afforded the new acylated iridoid glycosides, the new acylated rhamnopyranoses 9 and 10, in addition to ten known compounds. Premna odorata blanco lamiaceae is a medicinal plant traditionally used in albay province, in southeastern luzon, philippines to treat tuberculosis. Article pdf available in journal of medicinal plant research 5 july. It is one of the seven components of a commercialized philippine herbal preparation called pitopito. Metabolites free fulltext metabolomic profiling and. To evaluate the cytotoxic activities of premna odorata p. Anti microbial activities and phytochemical screening of.
Jun 11, 2014 premna odorata blanco lamiaceae is a medicinal plant traditionally used in albay province, in southeastern luzon, philippines to treat tuberculosis. It is widespread through tropical and subtropical regions in africa, southern asia, northern australia, and various islands in the pacific and indian oceans species. Lrhamnopyranosylcatalpol premnacorymboside a 1, was isolated from the flowers along with 10otranspmethoxycinnamoylcatalpol 3 and verbascoside. Use the decoction of leaves and flowering tops as a vaginal douche. We were grafting some premna microphylla wips to a premna odorata to improve its specie, specifically replacing its foliages with the ones that. Biological activity of natural products research papers. Isolation and characterization of antimicrobial, antiinflammatory and. Phytochemical investigation of premna odorata blanco lamiaceae young stems afforded four new acylated rhamnopyranoses 14, along with fourteen known compounds 519. Recently, in vitro and in vivo studies targeting its antituberculosis activity showed that p. Alagau premna odorata this fastgrowing native tree is very. In the philippines, a decoction of the leaves was considered as diuretic, carminative, and febrifuge and used for vaginal irrigation, coughs, beriberi.
Its medicinal uses, however, have not been scientifically validated. Premna odorata blanco, lamiaceae, popularly known as fragrant premna is a small tree native to temperate and tropical asia, including the philippines, and cultivated in different global locations. These cellfree antioxidant assays do not support the cellular physiological conditions, do not. Study on the chemical constituents of premna integrifolia l. Premna odorata is a shrub or small tree that usually grows up to 10 metres tall, occasionally to 12 metres. Madhusudana rao division of natural product chemistry, csir indian institute of chemical technology, tarnaka, hyderabad 500 607, telangana, india. Antitubercular constituents from premna odorata blanco. Phytochemical investigation of premna odorata blanco. Twentythree species and two varieties are enumerated, including seven endemic taxa. Acylated iridoids and rhamnopyranoses from premna odorata. The structures of the new compounds were confirmed using extensive 1d. On my recent trip, i saw it growing wild on the beaches of eastern taiwan.
These are primarily included because names of species rank are synonyms. Premna odorata herb uses, benefits, cures, side effects. Jul 28, 2015 we were grafting some premna microphylla wips to a premna odorata to improve its specie, specifically replacing its foliages with the ones that has the ability to reduce its leaf size significantly. Premna vestita schauer premna odorata, known as fragrant premna, is a species in the genus premna part of the family lamiaceae native to the indian subcontinent, yunnan, southeast asia, new guinea, and northern australia, and naturalized in southern florida 2. Pdf ethnomedicinal uses, phytochemistry and pharmacological. The bole can be up to 25cm, occasionally 30cm, in diameter 310. The genus premna contains 200 species under the family verbenaceaeall over the. The premna genus can be used traditionally in treating various ailments like rheumatism, asthma, dropsy, cough, fever, boils and scrofulous diseases. Join our friendly community that shares tips and ideas for gardens, along with seeds and plants.
Premna is perfect for most bonsai styles including literati, cascade, windswept, informal upright, forest and raft. Isolation and characterization of antimicrobial, antiinflammatory and chemopreventive flavones from premna odorata blanco article pdf available in journal of medicinal plant research 5. Alagaw is a tree that is only found in the philippines. Its natural growth pattern is to form a large tree with leaves 68 inches in length but these reduce greatly with proper bonsai care. Premna is a genus of flowering plants in the mint family, lamiaceae, first described for modern science in 1771. The extract of the leaves is helpful in healing wounds. Both the extracts of this plant showed effective free radical scavenging. Premna odorata helps in facilitating urination as it is diuretic in nature. The flavonoids showed potent antioxidative activities41.
A small tree rarely reaching 10 m, it is used as a source for traditional medicine in the philippines, and is planted occasionally as an ornamental there and. Pdf isolation and characterization of antimicrobial, anti. Premna odorata blanco, lamiaceae, popularly known as fragrant premna is a small tree native to temperate and tropical asia, including the philippines, and cultivated in different global locations lirio et al. The structures of new compounds were confirmed using extensive 1d, 2d nmr, and hresims analysis. Jan 23, 2017 premna odorata blanco verbenaceae or alagau is an endemic and a wellknown medicinal plants in the philippines. These results might be associated with the free position at c1 with the. Antibacterial and antioxidant activities of leaf extracts of. Premna odorata, known as fragrant premna, is a species in the genus premna part of the family lamiaceae native to the indian subcontinent, yunnan, southeast asia, new guinea, and northern australia, and naturalized in southern florida. In the philippines, the decoction of the leaves is used as a diuretic, a febrifuge, and for the treatment of vaginal irritation, coughs, abdominal pains, and dysentery. Philippine herbal medicine an illustrated compilation of medicinal plants in the philippines by dr godofredo stuart, with botanical information, chemical properties, folkloric uses and research studies. The genus premna lamiaceae, distributed throughout tropical and. Premna odorata, known as fragrant premna, is a species in the genus premna native to the. Premna microphylla is an extremely popular bonsai material used throught much of southeast asai.
The plant list includes 333 scientific plant names of species rank for the genus premna. Phytochemical investigation of premna odorata blanco, lamiaceae, leaves afforded three new acylated iridoid glycosides and two new acylated rhamnopyranoses 9 and 10, in addition to ten known compounds. This study aimed to determine the antitubercular property of the crude extract and subextracts of the leaves, and to isolate the bioactive principles from the active fractions. Premna odorata blanco verbenaceae or alagau is an endemic and a wellknown medicinal plants in the philippines. Alagau premna odorata this fastgrowing native tree is. Metabolomic profiling of different premna odorata blanco. Compounds associated with antiinflammatory and antinociceptive properties were previously isolated from its leaves. Keys, notes on their distributional and ecological data, vernacular names and some illustrations are also provided. Chew the root of this herb to resolve the cardiac problems. Jul 04, 2011 isolation and characterization of antimicrobial, antiinflammatory and chemopreventive flavones from premna odorata blanco article pdf available in journal of medicinal plant research 5. Triplenegative breast cancer suppressive activities. Various applications of the plant include its use as analgesic, antipyretic, and anti inflammatory. We do not intend the plant list to be complete for names of infraspecific rank. Flowers are greeninshwhite or nearly white, 45 mm long and borne on terminal inflorescences cymes 6820 cm in diameter.
Has a hard wood that can be used for jin and shari development. The fractions were tested for their cytotoxic activity against human colon cancer cell line hct116, breast cancer cell line mcf7, lung adenocarcinoma cell line a549 and chinese hamster. Ethnomedicinal uses, phytochemistry and pharmacological. It is common and widely distributed in the philippines at low altitudes and is widely known as alagao. Browse pictures and read growth cultivation information about fragrant premna premna odorata supplied by member gardeners in. Ethnomedicinal uses, phytochemistry and pharmacological aspects. For many years now, alagaw has been considered a drug in the philippines, being used to loosen phlegm and relieve coughs.
The different parts of the plant like leaves, stem, stem barks, root, root barks and wood have been used for extraction purpose. Phytochemical study on the plant premna integrifolia l. Premna odorata, premna pubescens, fragrant premna, alagaw. Lamiaceae in the flora malesiana area, kew bulletin 68. The acyclic monoterpenediol diesters, premnaodorosides a, b and c, isolated from premna odorata, were shown to be 3,7dimethyloctan1,8diol esterified with iridoid acid glucosides, namely two. View biological activity of natural products research papers on academia. Feb 2, 2018 alagau premna odorata this fastgrowing native tree is very tolerant to infertile and waterlogged soils. The atlas of florida plants provides a source of information for the distribution of plants within the state and taxonomic information. Philippine herbal medicine an illustrated compilation of medicinal plants in the philippines by dr godofredo stuart, with botanical information, chemical properties, folkloric uses. Premna odorata blanco verbenaceae is a native tree of the philippines where its leaves are used traditionally for vaginal irrigation and tuberculosis.
The website also provides access to a database and images of herbarium specimens found at the university of south florida and other herbaria. Pdf isolation and characterization of antimicrobial. Specifically, this study was conducted to determine the percent yield, antimicrobial activities and the secondary metabolites of alagaw leaf extract which was analyzed and it include alkaloid, anthraquinone, saponins and steroid. The researcher focused mainly to determine the antimicrobial properties and phytochemical screening of the alagaw leaf extract. It is widespread through tropical and subtropical regions in africa, southern asia, northern australia, and various islands in the pacific and indian oceans. Ars germplasm resources information network prod integrated taxonomic information system prod. The structures of the new compounds were confirmed using extensive 1d and 2d nmr analysis.
A synopsis of the genus premna in thailand is taxonomically revised. Media in category premna serratifolia the following 87 files are in this category, out of 87 total. The isolated compounds were tested for their cell proliferation and migration inhibition activities against the. Pdf antimicrobial activities and phytochemical screening of the.
Premna is placed under viticoideae subfamilia by grin and under lamiaceae incertae sedis subfamilia by ncbi. Metabolomic profiling and cytotoxic tetrahydrofurofuran. Premna odorata blanco fragrant premna subordinate taxa. Banahaw and in many other places in the philippines. Anti microbial activities and phytochemical screening of the. The structures of the new compounds were confirmed using extensive 1d, 2d nmr, and hresims analysis.
Study on the chemical constituents of premna integrifolia. Cytotoxic activity of crude extracts and fractions from. Pdf premna odorata blanco verbenaceae is a native tree of the. Chemical and molecular mechanisms of antioxidants experimental approaches and model systems. The plant list includes a further 77 scientific plant names of infraspecific rank for the genus premna. This study aimed to determine the antitubercular property of the crude extract and subextracts of the leaves, and to isolate the bioactive principles from the.
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